A iguana azul

Momento zen do meu dia:

“Once the SRP and its receptor have targeted a ribosome synthesizing
a secretory protein to the ER membrane, the ribosome
and nascent chain are rapidly transferred to the
translocon, a protein-lined channel within the membrane. As
translation continues, the elongating chain passes directly
from the large ribosomal subunit into the central pore of the
translocon. The 60S ribosomal subunit is aligned with the
pore of the translocon in such a way that the growing chain
is never exposed to the cytoplasm and does not fold until it
reaches the ER lumen (see Figure 16-6).”

in, Molecular Cell Biology; 5th Ed.; Lodish et al.